diff --git a/src/dynarmic/src/dynarmic/CMakeLists.txt b/src/dynarmic/src/dynarmic/CMakeLists.txt
index efae44d917..b74626bcd5 100644
--- a/src/dynarmic/src/dynarmic/CMakeLists.txt
+++ b/src/dynarmic/src/dynarmic/CMakeLists.txt
@@ -160,6 +160,10 @@ if ("A64" IN_LIST DYNARMIC_FRONTENDS)
 endif()
 
 if ("x86_64" IN_LIST ARCHITECTURE)
+    # Newer versions of xbyak (>= 7.25.0) have stricter checks that currently
+    # fail in dynarmic
+    target_compile_definitions(dynarmic PRIVATE XBYAK_STRICT_CHECK_MEM_REG_SIZE=0)
+
     target_compile_definitions(dynarmic PRIVATE XBYAK_OLD_DISP_CHECK=1)
     target_link_libraries(dynarmic
         PRIVATE