diff --git a/src/video_core/renderer_vulkan/vk_buffer_cache.cpp b/src/video_core/renderer_vulkan/vk_buffer_cache.cpp
index 6256bc8bd8..9f6ddb630e 100644
--- a/src/video_core/renderer_vulkan/vk_buffer_cache.cpp
+++ b/src/video_core/renderer_vulkan/vk_buffer_cache.cpp
@@ -555,7 +555,10 @@ void BufferCacheRuntime::BindVertexBuffer(u32 index, VkBuffer buffer, u32 offset
     if (index >= device.GetMaxVertexInputBindings()) {
         return;
     }
-    if (device.IsExtExtendedDynamicStateSupported()) {
+    const bool use_stride_dynamic = device.IsExtExtendedDynamicStateSupported() &&
+                                    !(device.IsExtVertexInputDynamicStateSupported() &&
+                                      Settings::values.vertex_input_dynamic_state.GetValue());
+    if (use_stride_dynamic) {
         scheduler.Record([index, buffer, offset, size, stride](vk::CommandBuffer cmdbuf) {
             const VkDeviceSize vk_offset = buffer != VK_NULL_HANDLE ? offset : 0;
             const VkDeviceSize vk_size = buffer != VK_NULL_HANDLE ? size : VK_WHOLE_SIZE;
@@ -595,7 +598,14 @@ void BufferCacheRuntime::BindVertexBuffers(VideoCommon::HostBindings<Buffer>& bi
     if (binding_count == 0) {
         return;
     }
-    if (device.IsExtExtendedDynamicStateSupported()) {
+    // Use BindVertexBuffers2EXT (with stride) only if:
+    // 1. VK_EXT_extended_dynamic_state is supported (provides VK_DYNAMIC_STATE_VERTEX_INPUT_BINDING_STRIDE_EXT)
+    // 2. AND VK_EXT_vertex_input_dynamic_state is NOT active (supported + enabled by toggle)
+    //    Because VIDS and BINDING_STRIDE are mutually exclusive in the pipeline
+    const bool use_stride_dynamic = device.IsExtExtendedDynamicStateSupported() &&
+                                    !(device.IsExtVertexInputDynamicStateSupported() &&
+                                      Settings::values.vertex_input_dynamic_state.GetValue());
+    if (use_stride_dynamic) {
         scheduler.Record([bindings_ = std::move(bindings),
                           buffer_handles_ = std::move(buffer_handles),
                           binding_count](vk::CommandBuffer cmdbuf) {